Management of challenging cases of patients with cancer-associated thrombosis including recurrent thrombosis and bleeding: guidance from the SSC of the ISTH.

M. CARR IER ,* A . A . KHORANA,† J . I . ZWICKER ,‡ S . NOBLE ,§ A. Y . Y . LEE ¶ and ON BEHALF OF THE SUBCOMMITTEE ON HAEMOSTAS I S AND MAL IGNANCY FOR THE SSC OF THE ISTH *Thrombosis Program, Division of Hematology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada; †Department of Solid Tumor Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH; ‡Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; §Royal Gwent Hospital, Newport, UK; and ¶Division of Hematology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada